Shipping Estimate
USA
- USA
- CAN
- USA
- CAN
Ships within 48 hours · Estimated delivery Jul 10 - Jul 15
Promo Codes Available:
For Your Every Summer RSVP, with Code: SUMMER15
Description
IL-3R alpha/CD123 His Tag Protein, CanineProduct Specification Species Canine Synonyms CD123 antigen; CD123; hIL3Ra; hIL 3Ra; IL 3 R alpha; IL 3 receptor subunit alpha; IL3R alpha; IL 3R alpha; IL 3R subunit alpha; IL3R; IL3RA; IL 3Ra; IL 3R alpha; IL3RAY; IL3RX; IL3RY; interleukin 3 receptor, alpha (low affinity); interleukin 3 receptor subunit alpha; MGC34174 Accession XP_038305195. 1 Amino Acid Sequence Ser33 Asp315, with C terminal His Expression System HEK293 Molecular Weight 43 55kDa
Product Specification
| Species | Canine |
| Synonyms | CD123 antigen; CD123; hIL3Ra; hIL-3Ra; IL-3 R alpha; IL-3 receptor subunit alpha; IL3R alpha; IL-3R alpha; IL-3R subunit alpha; IL3R; IL3RA; IL-3Ra; IL-3R-alpha; IL3RAY; IL3RX; IL3RY; interleukin 3 receptor, alpha (low affinity); interleukin-3 receptor subunit alpha; MGC34174 |
| Accession | XP_038305195.1 |
| Amino Acid Sequence | Ser33-Asp315, with C-terminal His |
| Expression System | HEK293 |
| Molecular Weight | 43-55kDa (Reducing) |
| Purity | ＞95% by SDS-PAGE &＞95% by SEC-HPLC |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Tag | His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, PH7.4, 5% trehalose |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
| Reference | 1. LIU, KEQIANG, ZHU, MENGRU, HUANG, YAO, et al. CD123 and its potential clinical application in leukemias [J]. Life sciences,2015,122(1):59-64. |
Background
Interleukin-3 receptor α (IL-3Rα) is the α subunit of the ligand-specific IL-3R and initiates intracellular signaling in response to IL-3. The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. IL-3 amplifies proinflammatory signaling and cytokine storm in murine sepsis models. In vitro, IL-3 stimulation promoted IL-3Rα proteasomal degradation dependent on RNFT2 (RING finger transmembrane-domain containing protein 2, also TMEM118), and we identified IL-3Rα lysine 357 as a ubiquitin acceptor site. Researches identify RNFT2 as a negative regulator of IL-3Rα and show a potential role for the RNFT2/IL-3Rα/IL-3 axis in regulating innate immune responses in the lung.
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy
4.1 ★★★★★
Based on 2013 reviews
Sort
Product Reviews
★★★★★ 4
Works fairly well! Smells good.
Scent: Sweet Peach & Nectar
This works really good, it has a sweet peach smell to it and lasts for most of the day. After a long day the sweat makes it smell odd to me as my partner doesn't notice a change. Ive only used it after my showers since im afraid it might change the smell if I reapply throughout the day. When i get a new one i will try that and update if it makes me smell decent still after a few uses or if it starts to stink.
It hasn't caused any irritation to my skin.
I do like how easy it is to roll both ways and it doesn't get stuck like most deodorants I've used. Though I dont like how it visibly sticks to my clothes as it takes a bit to dry.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on March 9, 2026
★★★★★ 5
LOVE it! Easy to use, pigment is perfect, lasts all day!
Color: Black Brown, Size: 0.01 Ounce (Pack of 2)
I am a victim of early childhood bullying by my brother, who used me for the butt of all his jokes. My eyebrows for one. Always saying they were so think, I looked like the character from the guy from the Muppets Bert or Ernie. Always pointing them out and ridiculing me in front of everyone. I was little and it got worse as I got older, so when I was in grade school, I got tired of it and got ahold of my older sister's Nair hair removal and took them off. Imagine being in fifth grade fat, ugly and no brows, the taunting got even worse, so I had to learn from a young age to draw them in, I went through hell!
Throughout the years, I learned how to draw them in and always used Jordana pencils as they were cheap and perfect. Since they no longer make them anyone, I went on the hunt for a better pencil, and after spending tons of money on eyebrow pencils and seeing how worthless they were, I tried these and OMG, FINALLY, someone got it right. These pencils are perfect, it's a self sharpening mechanical pencil so you don't loose half the pencil when trying to sharpen, It applies perfectly, the coverage is perfect, stays on forever, and removes with ease. One other thing that makes this pencil even more dynamic is the eraser at the end of the pencil, it allows you to shape your brows perfectly!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 25, 2026
★★★★★ 5
Sharp lines that don’t smudge
Color: Black, Size: 0.01 Ounce (Pack of 2)
This eyeliner is very precise and easy to apply, allowing you to create clean, sharp lines without much effort. The waterproof formula holds up well throughout the day without smudging or fading easily. It works well for both subtle everyday looks and more dramatic winged eyeliner styles. The built-in sharpener also helps maintain precision over time. Overall, it’s a dependable eyeliner for long-lasting eye definition.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 20, 2026
★★★★★ 5
Good value ! Worth the purchase 😉
Color: Bronze, Size: 0.01 Ounce (Pack of 1)
Love this eye liner , pretty liter brown color . Smooth aplication . Not smudgy at all, ☺️👍Blends nicely .Easy to remove . Always love this brand !
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 19, 2026
★★★★★ 4
Revlon colorstay pencil
Color: Sapphire, Size: 0.01 Ounce (Pack of 1)
This liner goes on well and has staying power. I like the color and am happy with this purchase, however… it needs to be sharpened just about every use. I probably won’t order again.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 27, 2026
recommand products
OUTLINE BASKET Set | Draht-OBSTKORB | Henry Julier | Areaware
141.00
10-16 Land Rover L319 LR4 Power Steering Pressure Hose Line AH223L600AA OEM
81.95
98-03 Jaguar XJR X308 Front Left or Right Shock Absorber Strut MND2141CD OEM
94.95
14-17 Range Rover Sport L494 Front Left Driver Seat Armrest Almond SVA OEM
120.35
Custom Family Drawing – Unique Printed Gift
27.00