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Description
ARIH1 Recombinant Rabbit mAb (S-3166-64)Product Specification Host Rabbit Antigen ARIH1 Synonyms E3 ubiquitin protein ligase ARIH1; H7 AP2; HHARI; Monocyte protein 6 (MOP 6); Protein ariadne 1 homolog (ARI 1); UbcH7 binding protein; ARI; MOP6; UBCH7BP Immunogen Synthetic Peptide Location Cytoplasm, Nucleus Accession Q9Y4X5 Clone Number S 3166 64 Antibody Type Recombinant mAb Isotype IgG Application WB, ICC Reactivity Hu, Ms, Rt, Mk Positive Sample HeLa, A431, MCF7, PC 3, NIH 3T3, C6, COS 7
Product Specification
| Host | Rabbit |
| Antigen | ARIH1 |
| Synonyms | E3 ubiquitin-protein ligase ARIH1; H7-AP2; HHARI; Monocyte protein 6 (MOP-6); Protein ariadne-1 homolog (ARI-1); UbcH7-binding protein; ARI; MOP6; UBCH7BP |
| Immunogen | Synthetic Peptide |
| Location | Cytoplasm, Nucleus |
| Accession | Q9Y4X5 |
| Clone Number | S-3166-64 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, ICC |
| Reactivity | Hu, Ms, Rt, Mk |
| Positive Sample | HeLa, A431, MCF7, PC-3, NIH/3T3, C6, COS-7 |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | Hu, Ms, Rt, Mk |
| ICC | 1:500 | Hu, Ms |
Background
ARIH1 (Ariadne RBR E3 ubiquitin-protein ligase 1) is a 557-amino-acid RING-between-RING (RBR) E3 ligase that ubiquitinates multiple substrates—most notably DNA-PKcs, whose proteasomal degradation activates the cGAS-STING pathway to enhance anti-tumor immunity, while in colorectal cancer it instead promotes K63-linked ubiquitination of PHB1 to drive mitochondrial respiration and tumor progression—thereby acting as a context-dependent regulator of proliferation, DNA repair, epithelial-mesenchymal transition and immune evasion through its dynamic interactions with E2 enzymes and cullin-RING ligase complexes.
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4.3 ★★★★★
Based on 1357 reviews
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Product Reviews
★★★★★ 5
Not 6 ft
Color: Grey, Size: 34" - 3 Panel
I bought this for filming my auditions. I am 5’4” .The height lists is 6 ft but the fabric only reaches 5’9 1/2 “!
when I must film myself head to toe, the top bars are showing. It’s easy to set up. But when I film I must tilt my camera to keep the top bars out of frame which is not acceptable.
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Reviewed in the United States on May 1, 2026
★★★★★ 4
Perfect for what I needed - getting a 2nd one.
Color: Black, Size: 22" - 4 Panel
Putting it together was a BEE-OTCH!! Yes, one of the tubes had the top cap installed at the wrong end (& getting it off required tools), and yes, stretching the fabric to get the screws in was incredibly hard...but am I buying another one? YES! After all is said and done, this is a great room divider. I opted out of installing the paddle feet & it still works perfect. It won't filter light all that great and even though it stands on its own, it can be blown over easily - but for the price? Excellent. If I wanted a heavy duty, thicker, more expensive one, I would've bought one.
The 2nd one is on the way.
Perfect height, no weird smell, nice and light and easy to move around.
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Reviewed in the United States on September 30, 2025
★★★★★ 5
WHERE HAVE YOU BEEN 😊
Color: Grey, Size: 34" - 3 Panel
I purchased RANTILA 3 Panel Room Divider, 6 Ft Tall Folding Privacy Screen Freestanding Room Partition Wall Dividers, 102''W x 20''D x 71''H, Grey. For outdoor use on my patio is perfect . PRIVACY!!! YAY!
It was packaged very carefully. There were no missing parts. Instructions were there but I still had to use the video visually. A few screws would not screw in. So I used a hammer with a few good taps that helped using the screw driver. 😊 It was easy putting it together following the directions. Everything is well made. Love the height, functionality and it’s definitely light it works.
Thank you
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Reviewed in the United States on June 7, 2025
★★★★★ 5
I am happy with the room divider. It does what I intended.
Color: Beige, Size: 34" - 3 Panel
Use a power screwdriver.
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Reviewed in the United States on April 25, 2026
★★★★★ 3
It’s really pretty decent except for one thing.
Color: Grey, Size: 34" - 4 Panel, Color: Grey, Size: 34" - 4 Panel
I bought two of these for my basement and they do look great. They were easy to assemble and I’m happy with them. The problem is that the stitching on the fabric panels are almost the size of a machine basting stitch (which for non sewers means large temporary stitches). Because the panels are tight by design, the stitches had already started to come undone before I could finish assembling everything. Fortunately I can sew and I reinforced all the panels. I had to take the first ones back off the poles to do them but I did the second set before assembling. It’s really not a bad product for the money. It’s quality fabric and the design itself looks great. The stitching looks fine but it’s just not substantial enough for the purpose it is supposed to serve. I can’t imagine why it be sewn so insufficiently. I was able to resolve my issue because I can sew. I wasn’t planning on sewing nor did I really have the time. I could have made it myself but I didn’t want to and that is why I purchased this. I ended up using valuable time. The really unfortunate thing is, I have no other complaints. This is a manufacturing problem.
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Reviewed in the United States on February 3, 2023
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