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Description
Rat Anti-Mouse CD3ε Antibody (S-3759)Product Specification Host Rat Antigen CD3 Synonyms T cell surface glycoprotein CD3 epsilon chain; T cell surface antigen T3 Leu 4 epsilon chain; Cd3e Location Cell membrane Accession P22646 Clone Number S 3759 Antibody Type Rat mAb Isotype IgG2a Application FCM Reactivity Ms Positive Sample C57BL 6 mouse splenocytes Purification Protein G Concentration 2 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS pH7. 4 Stability &
Product Specification
| Host | Rat |
| Antigen | CD3ε |
| Synonyms | T-cell surface glycoprotein CD3 epsilon chain; T-cell surface antigen T3/Leu-4 epsilon chain; Cd3e |
| Location | Cell membrane |
| Accession | P22646 |
| Clone Number | S-3759 |
| Antibody Type | Rat mAb |
| Isotype | IgG2a |
| Application | FCM |
| Reactivity | Ms |
| Positive Sample | C57BL/6 mouse splenocytes |
| Purification | Protein G |
| Concentration | 2 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS pH7.4 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied |
Dilution
| application | dilution | species |
| FCM | 1:200 | Ms |
Background
CD3ε protein, also known as CD3E, is a crucial component of the T-cell receptor (TCR) complex, which is essential for T-cell activation and function. It is a single-pass type I membrane glycoprotein that contains one Ig-like domain and one immunoreceptor tyrosine-based activation motif (ITAM) domain. CD3ε, along with CD3γ, CD3δ, and CD3ζ, forms the TCR-CD3 complex, which plays a vital role in coupling antigen recognition to intracellular signal-transduction pathways. This protein is essential for the proper development of T-cells and is involved in the internalization and downregulation of the TCR-CD3 complex on the cell surface. Defects in the CD3ε gene can lead to severe immunodeficiency and have been linked to a susceptibility to type I diabetes in women.
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4.7 ★★★★★
Based on 171 reviews
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Product Reviews
★★★★★ 2
Has Potential, Poorly Executed
Format: Kindle
I really really wanted to enjoy this book and was looking forward to reading it. However there were just one too many convoluted plot points, sentences just did not flow nicely at times, and I was left with a lot of confusion on my end. I think it has the bones of being a great story but seems like it was rushed and I had to push myself to finish the last of the book and was left with an unsatisfying ending. It’s definitely different from other omegaverse novels I’ve read but not for good reasons. I really think it could be great but needs some serious tweaking and editing before I’d read it again.
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Reviewed in the United States on February 3, 2025
★★★★★ 5
Secrets, Seduction, and Rockstars!
Format: Kindle
Rockstars, secrets, and off-the-charts chemistry? Sign me up!
Cinder Blaze takes us on a rollercoaster of passion and peril with Knot Their Omega. Blair Vesper, a secret Omega masquerading as an Alpha, strikes a risky deal to tour with Blooming Salvation, a band teetering on the edge of chaos. Enter Icarus Morrigan, the enigmatic manager, and his three complicated and irresistibly sexy rockstars: wild Kenji, icy Kaiser, and fiery Nathaniel.
This book delivers steamy Omegaverse drama, sizzling slow-burn romance, and just the right dash of angst. The tension between Blair and the band crackles like electricity onstage, while the societal stakes add depth to the spicy dynamics.
Short, sharp, and oh-so-sinful Knot Their Omega will have you hooked from the first note!
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Reviewed in the United States on December 9, 2024
★★★★★ 5
Addicting!
Format: Kindle
I could not stop reading. It was so refreshing to have a series start so completely different than most fated mates/fantasy academy rh I’ve been reading. From the desert scenery to the magic and feeding plus the psychological trauma the characters are there to deal with. Pandora is absolutely adorable and I totally relate to hiding behind my hair. I love that she’s literally the most scary type of demon but it’s not the usual “badass mc” persona (which I do love a badass that can fend for herself and kick ass from the start but it was a nice change of pace). I’m not usually a big fan of bully within the harem but each character has their reasons for their actions and also conflicting feelings about them. I adore Dex and Reed! Complete opposites but their personalities and inner monologues made them instant favs. I can’t wait to see the character growth with the guys and continued strength for Pandora.
The captivating characters and references to the Fate Hallow series added so much depth and now I need another reread while I wait for book 2. The concept of magic and the unique feeding habits of the demon characters were intriguing. I can't wait for the next book to continue this thrilling journey.
In summary, this book is a must-read for fantasy and magic academy rh fans. With its enchanting characters, nods to the Fate Hallow series, and imaginative concepts, it offers an immersive reading experience that hwill leave you craving for more.
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Reviewed in the United States on June 5, 2024
★★★★★ 4
Best academy I've read this year
Format: Kindle
I need a few things when it comes to a first book of a PNR romance series
1-Good world building (which this totally did)
2-An FMC I can root for (oh hell yes, Pandora is someone I can cheer for)
3-Good drama (can you say GROVEL BOYS!)
4-Enough story to make you feel like you really read something with meat (you saw this book is like 600 pages, yeah?)
5-A hook at the end so I want more! (please, Lyra, gimmie more?!? I need more!!)
Be aware this book is a slow burn, but damn do I feel like there'll be some big payoff when it finally happens. Who doesn't like the buildup?
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Reviewed in the United States on June 4, 2024
★★★★★ 5
Pandora’s Pain, Power, and Passion
Format: Kindle
I absolutely love this new world Lyra Winters has created! The spin on a Demon Academy setting was fresh, unique, and completely addictive.
Pandora is a character who immediately captured my heart. Thought to be powerless and enduring years of brutal abuse from her mother, it’s no surprise that her powers emerge at the exact moment she needs them most. After her mother’s death, Pandora discovers her father is none other than Death himself, a soul eater with a dark legacy. Her journey at the academy is anything but easy, filled with challenges tied to her father’s infamous reputation, her barely controlled abilities, and the cruelty of those around her.
Pandora is easy to root for, you feel every ounce of her pain, resilience, and growth. Along the way she meets Reed, a half-human dream demon who’s kind, steady, and the kind of friend everyone wishes they had. There’s also Hunter, a vengeance demon and counselor connected to her father, who adds another intriguing layer to her story. Then there are the bullies: Dexter, a brooding shadow demon; Bram, a chaos demon with a drinking problem and deep hatred for demon nobility; and Skel, a fear demon wrestling with his own darkness. They might hurt her, but they also can’t seem to stay away when she’s in danger, making for some deliciously complicated dynamics.
This book hits so many of my favorite tropes: friends to lovers, enemies to lovers, and of course, the irresistible “who hurt you?” storyline. I devoured it, and I’m already diving straight into book two!
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Reviewed in the United States on September 4, 2025
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