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Description
Biotinylated FcRn His&Avi Tag Protein, CynomolgusProduct Specification Species Cynomolgus Synonyms FcRn; FCGRT & B2M Accession Q8SPV9(FcGRT)Q8SPW0(B2M) Amino Acid Sequence Ala24 Ser297 (FcRn); Ile21 Met119 (B2M), with C terminal His and Avi tag Expression System HEK293 Molecular Weight 33 40 &10 15kDa (Reducing) Purity 95% by SDS PAGE Endotoxin <1EU g Conjugation Biotin Tag Avi Tag, His Tag Physical Appearance Lyophilized Powder Storage Buffer PBS, pH7. 4. Reconstitution Reconstitute at 0. 1 1 mg ml
Product Specification
| Species | Cynomolgus |
| Synonyms | FcRn; FCGRT & B2M |
| Accession | Q8SPV9(FcGRT)、Q8SPW0(B2M) |
| Amino Acid Sequence | Ala24-Ser297 (FcRn);Ile21-Met119 (B2M), with C-terminal His and Avi tag |
| Expression System | HEK293 |
| Molecular Weight | 33-40 &10-15kDa (Reducing) |
| Purity | ＞95% by SDS-PAGE |
| Endotoxin | <1EU/μg |
| Conjugation | Biotin |
| Tag | Avi Tag, His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, pH7.4. |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
| Reference | 1. Roopenian D. et al. (2007) FcRn: the neonatal Fc receptor comes of age. Nat Rev Immunol. 7: 715-725. |
Background
FcRn is an unusual Fc receptor, the biological importance of which is only beginning to be fully appreciated. In addition to its critical role in the transfer of maternal IgG to the fetus or neonate, FcRn is the homeostatic receptor responsible for extending the serum half-life of IgG in adults. The exact site(s) of IgG protection from degradation has not been delineated in vivo, but both endothelial cells and bone-marrow-derived cells can extend the serum persistence of IgG. FcRn is also expressed in many other tissues in the adult animal, including barrier sites such as the blood–brain interface, the glomerular filter in the kidneys and the intestinal epithelium. FcRn expression at these sites merits further study with the goals of modulating specific IgG transport to promote host defence or to control immune-complex deposition.
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4.7 ★★★★★
Based on 1818 reviews
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Product Reviews
★★★★★ 5
My Go-To Toner After Trying Many Others
Scent: Unscented, Size: 12 Fl Oz (Pack of 1)
I’ve tried many toners over the years, including higher-end brands, and this one continues to stand out for both performance and price. It does exactly what I need without unnecessary extras.
The formula feels gentle and effective, and I really appreciate that it’s alcohol free and fragrance free. Those two things are especially important to me, and this has been the only toner I’ve felt comfortable using during pregnancy. It doesn’t irritate my skin and fits easily into my daily routine.
Despite the affordable price, it performs just as well—if not better—than many more expensive options I’ve used in the past. My skin feels clean and refreshed after using it, without any tightness or residue.
Overall, this is a reliable, no-nonsense toner that delivers great results at a very reasonable price. If you’re looking for a simple, fragrance-free option that works well without breaking the bank, this is an easy recommendation.
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Reviewed in the United States on January 9, 2026
★★★★★ 5
Liquid facial magic!
Scent: Coconut Water, Size: 12 Fl Oz (Pack of 1)
I love this stuff. I use it daily as part of my facial routine and it has become one of those products I don’t even think about anymore because it just works.
It smells good without being overpowering and does a great job of helping control excessive oil buildup on my face. Nothing harsh, nothing drying, just clean and refreshed skin. Right after using this, I follow up with a facial moisturizer and the combo works beautifully. My skin feels balanced instead of tight or angry, which is exactly what I’m going for.
I know the label says men can use this as an aftershave, but that’s a hard pass for me. I stick to soothing, purpose-built post-shave products, specifically from Wholly Kaw. That stuff smells like it was handcrafted by skincare deities who truly care about your face. This toner is staying firmly in the “daily skincare” lane, where it shines.
Another big plus is how gentle it is. No burning, no weird tingling, no regret. Just a calm, refreshing step that makes my skin feel like it’s being treated with respect.
And the price? Under $10. That alone keeps me coming back. Honestly, I think they could charge a few dollars more for how well this performs, but I won’t complain about paying less for fantastic facial liquid magic.
Simple, effective, affordable, and a permanent part of my routine. My face approves.
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Reviewed in the United States on December 21, 2025
★★★★★ 5
THAYERS Lavender Witch Hazel Toner: Time-Tested Elegance in a Bottle!
Scent: Lavender, Size: 12 Fl Oz (Pack of 1)
Embarking on a journey down memory lane with THAYERS Lavender Witch Hazel Facial Toner has been nothing short of a delightful reunion. This timeless brand, known since my youth, has proven its mettle yet again. Let's dive into the aromatic, moisturizing wonder that is the Lavender Witch Hazel Toner:
Quality Infused with Elegance (5/5): THAYERS brings a touch of timeless elegance to skincare, and this lavender-infused toner is no exception. The quality is unmistakable, leaving my skin feeling pampered and rejuvenated after each use.
Cleansliness at its Best (5/5): The toner's prowess in cleansing is unparalleled. It effortlessly removes dirt and impurities, unveiling a refreshed and squeaky-clean complexion. My skin thanks me for this daily ritual of cleanliness.
Moisturizing Magic (5/5): The moisturizing effect is like a gentle caress for the skin. Unlike some toners that leave your face feeling parched, THAYERS Lavender Toner ensures that my skin is not just clean but incredibly moisturized after every application.
Refreshing Elixir (5/5): Ah, the refreshing burst of lavender! While opinions on the strength of the scent may vary, I find the lavender notes to be a delightful touch. The toner rejuvenates not just my skin but also my senses, making each application a mini spa moment.
Better than the Expensive Competitors (5/5): Sometimes the best things come in unassuming packages. Users have attested that this toner outshines even pricier competitors, proving that quality doesn't always have to break the bank.
Mixed Durability Verdict (4/5): Opinions are divided on durability, but for me, the overall benefits outweigh any minor considerations. The toner's efficacy in daily use makes it a staple in my skincare routine.
Generations-Long Trust (5/5): THAYERS is a brand that has stood the test of time, transcending generations. Its legacy of trustworthiness extends beyond my own experience, connecting with others who have relied on its skincare wonders.
Lavender Scent Aspiration (4/5): While I had hoped for a stronger lavender scent, the subtle notes are still a pleasant addition to my skincare ritual. The product's efficacy compensates for any scent expectations.
In conclusion, THAYERS Lavender Witch Hazel Facial Toner is a testament to the enduring charm of a trusted brand. Its quality, cleanliness, and moisturizing benefits make it a staple in my skincare routine and a connection to the past. Whether you're a longtime fan or a newcomer, this toner is a timeless treasure for your skin. Cheers to THAYERS for continuing to deliver skincare excellence!
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Reviewed in the United States on February 17, 2024
★★★★★ 5
Lasts awhile! Good product
Scent: Rose Petal, Size: 12 Fl Oz (Pack of 1)
Cleans without overdrying. Leave skin feeling clean, no stickiness. Pleasant light scent that doesn't linger. I get my moister from other products so this one idk if it moisturizes by itself. Good value for the money, you get a lot so it lasts awhile.
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Reviewed in the United States on May 10, 2026
★★★★★ 4
Love! Smell is nice, helps with dry skin
Scent: Cucumber, Size: 12 Fl Oz (Pack of 1)
I have been using Thayers for years. My skin is sooo dry and tight post shower. I put this in a small mister bottle, and Mist my face.
Scalp- my scalp gets itchy, I use this, witch hazel, apple Cider Vinegar and water in a dropper. Works amazing!
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Reviewed in the United States on March 24, 2026
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