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Description
The Malaria Genome Projects: The: PromiseThe year 2012 marks the tenth anniversary of the announcement of the genome sequence of the human malaria parasite Plasmodium falciparum and that of its mosquito vector Anopheles. The genome sequences were a result of the Plasmodium falciparum Genome Project. This book covers in detail the biology of malaria parasites and the mosquitoes that transmit the disease, how the Genome Projects came into being, the people who created them, and the cadre of
The year 2012 marks the tenth anniversary of the announcement of the genome sequence of the human malaria parasite Plasmodium falciparum and that of its mosquito vector Anopheles. The genome sequences were a result of the Plasmodium falciparum Genome Project.This book covers in detail the biology of malaria parasites and the mosquitoes that transmit the disease, how the Genome Projects came into being, the people who created them, and the cadre of scientists who are attempting to see the promise of the Projects realized. The promise was: a more complete understanding of the genes of the parasite (and its vector) would provide a rational basis for the development of antimalarial drugs and vaccines, allow a better understanding of the regulation of the complex life cycle in the red blood and liver cells of the human, identify the genes the parasite uses to thwart the host immune response and the ways in which the parasite evades cure by drug treatments, as well as leading to more effective measures of control transmission. The hope was that cracking the genetic code of Plasmodium and Anopheles would reveal the biochemical Achilles heel of the parasite and its vector, leading to the development of novel drugs and better methods of control, and by finding the targets of protective immunity could result in the manufacture of effective vaccines.Through a historic approach, this book will allow for those new to the field, or those with insufficient background in the sciences, to have an easier entry point. Even scientists already working in the field may better appreciate how discoveries made in the past can impact the direction of future research.Shipping Notes
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4.9 ★★★★★
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★★★★★ 5
Don't be in a hurry
Format: Hardcover
A fine winter read...maybe two or three winters. Very detailed history.
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Reviewed in the United States on October 9, 2025
★★★★★ 5
My review
Format: Hardcover
Very good, fitting end of the N.A.M. Rodgers trilogy.
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Reviewed in the United States on April 10, 2026
★★★★★ 5
Answers Many Questions about Naval Developments
Format: Hardcover
The history offers a detailed and well organized account of the Royal Navy as it transitioned from sail to steam. Coverage included personalities, technology, tactics and strategy. The combination provided a complete appreciation of the dynamics at play, some unexpectedly. The details might be a bit much for a casual reader but offered plenty of avenues for research not available or compiled in one source. I look forward to the final volume, which should describe another watershed era.
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Reviewed in the United States on February 20, 2026
★★★★★ 5
Great Book with a different perspective
Format: Hardcover
This will be a short review of a very long book. I ordered the book expecting more of a history of the British Navy, but this is more of a history of Britain with respect to its navy. It is still excellent and authoritative, just different than I expected. I really appreciate a somewhat different perspective than I have found in some other books. For example, any discussion of Jackie Fisher I have read previously seemed to border on the hagiographic, whereas here he seems to get a very evenhanded appraisal. A great book, highly recommended.
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Reviewed in the United States on November 17, 2025
★★★★★ 5
Great read about naval history
Format: Hardcover
Great book completing a Trilogy ofBritish Naval history. Great read!
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Reviewed in the United States on July 11, 2025